Interpol has announced one of the largest synthetic drug seizures in history, adding it intercepted enough fentanyl to kill 151 million people.
Interpol's Operation Lionfish–Mayag III has led to the seizure of 76 tonnes of narcotics worth $6.5 billion.
An international operation against drug trafficking has led to massive seizures of synthetic drugs valued at USD 6.5 billion.
— INTERPOL (@INTERPOL_HQ) September 16, 2025
Authorities intercepted a total of 76 tonnes of drugs, including 51 tonnes of methamphetamine along with fentanyl, heroin, cocaine, & chemical precursors. pic.twitter.com/J9ZlxTnLSz
The operation took place between June 30 and July 13, with a co-ordinated crackdown spanning 18 countries in Asia and North America.
A record 297 million methamphetamine tablets was confiscated, along with massive quantities of fentanyl, heroin, cocaine, and precursor chemicals used in drug manufacturing.
Officials foiled traffickers’ attempts to conceal narcotics inside everyday household items like tea boxes, cat food packets, espresso machines, and surfboards.
Interpol Secretary General Valdecy Urquiza said in a statement: ‘The drugs trafficked by transnational criminal networks fuel violence, cripple economies and endanger public health. Each successful seizure highlights the power of law enforcement working together to protect lives and dismantle these threats. We will continue co-ordinating global efforts to support our member countries in safeguarding communities.’
A total of 386 arrests were made during the operation. Interpol also dismantled several trafficking rings and criminal networks operating on the darknet.